Python AI agent frameworks (2026)
Agent frameworks and SDKs whose listings say they are built for Python. Here are all 15 from the AgentScout directory.
Updated
How we picked and ranked: tools are matched by category, the pricing each maker states and what each tool says it does. They are ranked by GitHub stars as recorded on each listing (link checks 2026-10-21); tools without a tracked repo follow, by listing maturity. No paid placements.
1. Agno
Python framework and runtime for building, running and managing multi-agent systems with memory, knowledge and tools.
Pricing (as stated): Open source + cloud · Mature
2. OpenAI Agents SDK (Python)
OpenAI's Python SDK for building multi-agent workflows; v0.23.0/0.23.1 released Oct 1-2.
Pricing (as stated): Open source · Mature, official SDK
3. Pydantic AI
Type-safe Python agent framework from the Pydantic team.
Pricing (as stated): Open source · Mature
4. RocketRide
AI pipeline engine with a C++ core and 50+ Python nodes for building, debugging and deploying LLM workflows and agents from VS Code or the CLI.
Pricing (as stated): Open source · Mature
5. Microsoft Agent Framework
Microsoft's framework for building and orchestrating agents and multi-agent workflows in Python and .NET.
Pricing (as stated): Open source · Mature
6. Strands Agents
Strands open-source SDK for building production agent harnesses in Python and TypeScript.
Pricing (as stated): Open source · Mature
7. Claude Agent SDK (Python)
Anthropic's Python SDK for building agents on Claude Code's agent loop, with the CLI bundled, custom tools and hooks.
Pricing (as stated): Open source · Mature
8. Upsonic
Python framework for building autonomous AI agents.
Pricing (as stated): Open source · Mature
9. Genkit
Google's open-source framework for building agentic apps in JavaScript, Go, Dart and Python.
Pricing (as stated): Open source · Mature
10. Marvin
Python library from Prefect for building AI agents and structured LLM workflows.
Pricing (as stated): Open source · Mature
11. Langroid
Python framework for multi-agent programming with LLMs.
Pricing (as stated): Open source · Active
12. Antigravity SDK
Google's Python SDK for building stateful AI agents powered by Antigravity and Gemini, abstracting the agent loop and runtime.
Pricing (as stated): Open source · Active
13. BeeAI Framework
Framework for building production-ready agents and multi-agent systems in Python or TypeScript.
Pricing (as stated): Open source · Active
14. Mirascope
Lightweight Python library for calling any LLM with typed outputs and tools through one interface, without a heavy framework.
Pricing (as stated): Open source · Active
15. Dynamiq
Python orchestration framework for building agentic and RAG applications from reusable nodes and workflows.
Pricing (as stated): Open source · Active
FAQ
What are the best Python AI agent frameworks?
Ranked by tracked GitHub stars, the top Python AI agent frameworks in our directory are Agno, OpenAI Agents SDK (Python), Pydantic AI, RocketRide, Microsoft Agent Framework. Stars measure popularity, not fit, so compare a few against your own task.
How many Python AI agent frameworks does AgentScout list?
15 tools match. This page shows the top 15. Pricing mix on this page: Open source (14), Open source + cloud (1).
How much do these tools cost?
Pricing is what each maker states on their site. Open-source tools are free to self-host but may need a paid model API key or offer paid cloud plans; freemium tools have a free plan with limits. Check each official site.
Where can I see every tool for building AI agents?
Our task page lists all 247 tools we match to building AI agents.
Related: All tools for building AI agents · Best AI Agent Frameworks · frameworks (15)
Similar searches: Open-source AI agent frameworks · TypeScript and JavaScript AI agent frameworks · Multi-agent frameworks
By role: For AI engineers
All popular searches · AI agents by role · Free tools
Related categories: Frameworks
Facts come from our directory listings; pricing is as each maker states it and can change. Check official sites before you choose.